Gregory JEDD, Ph.D, Principal Investigator

Gregory Jedd earned his bachelors degree in biology at the Foothill Community College and Stanford University. He received his PhD from the University of Chicago and did his postdoctoral work in Nam-Hai Chua’s lab at the Rockefeller University where he began to develop Neurospora crassa as a model system for cellular biology.  In September of 2004 he moved to Singapore to establish an independent research group.

You may wish to contact Dr Gregory JEDD at:
Tel: (65) 6872 7000, 6872 7708 or 6872 7709(DID) Email: gregory@tll.org.sg

For information on PhD studies at TLL, click HERE

Research Interests

  • Biogenesis of cellular organelles
  • Organelle inheritance and abundance control
  • Fungal Woronin bodies
  • Cellular evolution
  • Synthetic biology

Research Projects

We use the genetically amenable filamentous fungus Neurospora crassa as a model organism and focus on basic questions concerning eukaryotic organelle biogenesis, segregation and abundance control. Our primary approach utilizes forward genetics, followed by a secondary phase where we seek mechanistic insight based on a multidisciplinary approach that combines the power of haploid genetics with molecular genetic, microscopic, biochemical and computational methods. We are especially interested in the mechanisms that control the composition and abundance of cellular organelles and understanding how these are coordinated with multicellular development. One long-term goal of the lab is to use the knowledge derived from these studies to build customized cellular organelles that encapsulate useful structural and enzymatic assemblies. In addition, by focusing on unique aspects of the fungal cell, our work can foster new strategies for combating fungal pathogens.