In-Cheol JANG, Ph.D, Principal Investigator

Dr In-Cheol Jang graduated in genetic engineering from University of Suwon and completed his master’s study and obtained his PhD from Myongji University in Korea, where he studied on rice biotechnology. He joined the Prof. Chua lab at the Rockefeller University in 2003 first as a post-doctoral fellow (2003-2008) and subsequently as a research associate (2008-2012), where he investigated and unravelled mechanisms regulating light signaling in plants. In August 2012, he joined Temasek Life Sciences Laboratory (TLL) as an Assistant Director (SRP).

You may wish to contact Dr In-Cheol JANG at: Tel:(65) 6872 7409 or 6872 7093 (lab) Email: : jangi@tll.org.sg

 

For information on PhD studies at TLL, click HERE

Research Interests

  1. Plant secondary metabolites
  2. Metabolic engineering of terpenoids in plants
  3. Regulated proteolysis and protein stability in plants

Research Projects

1) Economical production of sweeteners, steviol glycosides in Stevia

The health concerns with artificial sweeteners have triggered recent interest in natural non-caloric sweeteners, one of which is derived from the plant Stevia. Leaves of Stevia rebaudiana Bertoni produce steviol glycosides (diterpene glycosides) that range in sweetness from 200-300 times as sweet as cane sugar. In contrast to artificial sweeteners such as cyclamate, saccharin, sucralose and aspartame, steviol glycosides are all natural and can be used primarily as a non-calorie sweetener and/or flavor enhancer.

Stevia rebaudiana (Bertoni) is a plant belonging to the Asteraceae (Compositae) family and is native to subtropical regions of Paraguay. It is grown as a perennial crop and an obligate short day plant with a critical day length of about 13 hr. This plant has been cultivated and used in Paraguay for over 500 years, in Japan since 1970s, in EU since 1989, and even in the USA since 1995.

Using Stevia as a natural sweetener plant, our research

  1. Study regulatory control of genes and enzymes involved in the steviol glycosides production .
  2. Establish Stevia capable of metabolic re-engineering for high-quantity and/or high-quality production of steviol glycosides.
  3. Identify key regulatory genes such as transcription factor genes controlling biosynthesis of steviol glycosides.
  4. Develop platform technologies for high-throughput functional genomics in Stevia.
2)      Metabolic engineering of aromatic plant, the mint family to produce plant essential oil, menthol