Publications

Wang, C, R Lu, X Ouyang, MWL Ho, W Chia, F Yu and KL Lim: Drosophila Overexpressing Parkin R275W Mutant Exhibits Dopaminergic Neuron Degeneration and Mitochondrial Abnormalities. The Journal of Neuroscience 27: 8563-8570 (2007).

Wang, H, GW Somers, A Bashirullah, U Heberlein, F Yu and W Chia: Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts. Genes & Development 20: 3453-3463 (2006).

Yu, F, CT Kuo and YN Jan: Drosophila Neuroblast Asymmetric Cell Division: Recent Advances and Implications for Stem Cell Biology. Neuron 51: 13-20 (2006).

Ng T, F Yu and S Roy: A homologue of the vertebrate SET domain and zinc finger protein Blimp-1 regulates terminal differentiation of the tracheal system in the Drosophila embryo. Development Genes and Evolution 216: 243-252 (2006).

Wang, H, KH Ng, H Qian, DP Siderovski, W Chia and F Yu: Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins. Nature Cell Biology 7: 1091-1098 (2005). (“News and Views”in Nature Cell Biology 7: 1047-1049 (2005); “Research Highlight”in Nature Reviews Molecular Cell Biology 6, in press)

Yu, F, H Wang, H Qian, R Kaushik, M Bownes, X Yang and W Chia: Locomotion defects, together with Pins, regulates heterotrimeric G-protein signaling during Drosophila neuroblast asymmetric divisions. Genes & Development 19: 1341-1353 (2005).

Wei, SY, LM Escudero, F Yu, LH Chang, LY Chen, YH Ho, CM Lin, CS Chou, W Chia, J Modolell and JC Hsu: Echinoid is a Component of Adherens Junctions that Cooperates with DE-Cadherin to Mediate Cell Adhesion. Developmental Cell 8: 493-504 (2005).

Yu, F: Analysis of the roles of Pins and heterotrimeric G proteins in asymmetric division of Drosophila neuroblasts. Methods in Enzymology 389, 364-382 (2004).

Yu, F, Y Cai, R Kaushik, X Yang and W Chia: Distinct roles of Gαi and Gβ13F subunits of the heterotrimeric G protein complex in the mediation of Drosophila neuroblast asymmetric divisions. The Journal of Cell Biology 162:623-33 (2003). (“In This Issue” in The Journal of Cell Biology 162: 531 (2003))

Kaushik, R, F Yu, W Chia, X Yang and S Bahri: Subcellular localization of LGN during mitosis: Evidence for its cortical localization in mitotic cell culture systems and its requirement for normal cell cycle progression Molecular Biology of the Cell 14: 3144-3155 (2003)

Yu, F, X Morin, R Kaushik, S Bahri, X Yang and W Chia: A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts. Journal of Cell Science 116: 887-96 (2003).

Cai, Y, F Yu, W Chia and X Yang: Apical complex genes control mitotic spindle geometry and the relative size of the daughter cells in Drosophila neuroblast and pI asymmetric divisions. Cell 112: 51-62 (2003).

Yu, F, CT Ong, W Chia and X Yang: Membrane targeting and asymmetric localization of Drosophila Partner of Inscuteable are discrete steps controlled by distinct regions of the protein. Molecular and Cellular Biology 22: 4230-4240 (2002). (Cover Article)

Chia, W, Y Cai, X Morin, M Tio, G Udolph, F Yu and X Yang: The cell cycle machinery and asymmetric cell division of neural progenitors in the Drosophila embryonic central nervous system. Novartis Foundation Symposia 237:139-51; discussion 151-63. Review (2001).

Yu, F, X Morin, Y Cai, X Yang and W Chia: Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in Inscuteable apical localisation. Cell 100: 399-409 (2000). (Minireviews in Cell 100: 599-602 (2000); Dispatch in Current Biology 10: R265-R267)